Precise 2D Gel Electrophoresis for Pharma Research: A Breakthrough in Protein Analysis
Precision is all
about the pharmaceutical world, with fast movement. New drug development is
contingent upon actual understanding of proteins involved in the disease as
well as in treatment. And this is precisely where 2D Gel Electrophoresis plays
a crucial role. Kendrick Labs, Inc. is the company which specializes in
providing precise and reliable protein analysis for pharmaceuticals, academia,
and related industries. Our expertise in 2D Gel Electrophoresis enables
researchers to gain the highest critical insights in such protein structures
and post-translational modifications as well as expression patterns that plays
a crucial role in drug development.
What is 2D Gel Electrophoresis?
2D Gel
Electrophoresis is a very efficient method of separating proteins based on two
independent characteristics: isoelectric point (pI) and their molecular weight.
In the first dimension, proteins are separated based on their pI during isoelectric
focusing. Separation based on molecular weight is done using SDS-PAGE in the
second dimension; separating proteins based on molecular weight. Dual
separation thus separates complex protein mixtures into distinct protein spots
for good information about the expression, modification, and interaction of
proteins.
At Kendrick Labs, Inc., we use
only the best equipment and proprietary protocols in pursuit of robust and
reproducible results from 2D Gel Electrophoresis. Whether you want to know how
potential drug candidates might affect the expression of your proteins of
interest or want to identify those biomarkers that implicate diseases, we give
you professional service that gives you the best data quality for your
research.
Significance of 2D Gel Electrophoresis in Pharma Research
In addition, in the
pharmacy industry, protein analysis has a critical role at every step of
pharmaceutical development, including target identification and clinical
testing. For example, two-dimensional gel electrophoresis allows the monitoring
of slight variations in protein expression levels, post-translational
modifications, and interactions that may affect drug efficacy and safety.
Among its greatest
benefits, this type of 2D Gel Electrophoresis can separate very complex mixtures
of proteins with very high resolution. This technique is invaluable for
studying protein expression in biological samples due to the fact that it can
analyze even thousands of proteins present in a tissue or blood specimen. The
uniqueness of this technique is that it allows separation of proteins using two
different separation criteria: their isoelectric point and molecular weight,
thus making it easier to focus on certain proteins that may be implicated in a
disease process or particular therapeutic mechanism.
For example, 2D Gel
Electrophoresis is widely used in the identification of biomarkers—proteins
that may serve as markers of disease or drug response. Reliable biomarkers
should be identified to be employed in approaches to personal medicine where
the treatments are tailored to the individual protein profile of the patient.
On the other hand, through 2D Gel Electrophoresis, researchers have been able
to gain insight into how drugs affect the expression and modification of
proteins, which also enables them to alter the formulations of drugs in search
of the optimal therapeutic application.
Why choose Kendrick Labs, Inc. as
your one-stop protein analysis solution?
With more than
three decades of experience in providing protein analysis services to the
pharmaceutical industry, academia, and a wide range of other industrial
divisions, Kendrick Labs, Inc. is the perfect destination for superior results
in such analyses. Advanced technologies, including 2D Gel Electrophoresis, are
used to ensure accurate and actionable information. We believe drug discovery
relies considerably on working with reliable data, and we provide that with
accuracy and help drive forward our clients' research goals.
Here's why Kendrick Labs, Inc. stands apart:
Precision and Accuracy: We use high-tech technology along with very
stringent quality control to ensure accuracy in each experiment. The 2D Gel
Electrophoresis services are provided for detailed, repeatable protein profiles
that meet the pharma research requirements.
Tailor-made Solutions: Since every
research project is unique, we offer protein analysis services that are
tailored to the needs of our clients. Whether drug discovery is at the early
stages or advanced stages and even into clinical trials, we would deliver
appropriately customized solutions to fit your requirements.
Professional Consultation: Still not
sure on how to approach your protein analysis research? Just talk to us; we are
here to help you through every phase of this process, from designing an experiment
to interpretation of results.
Fast Turnaround Times: We know the urge
for speed in pharmaceutical research. That's why we provide professional
services with very quick turnaround times without sacrificing the quality
needed. Free quotes and consultancy can be availed to devise research and
budgeting.
Detailed Data Analysis: We do 2D Gel Electrophoresis but also
comprehensive data analysis for our clients. We help them go through the
results obtained, identify proteins of interest, and harvest insights that will
drive forward your research.
The Future of Pharma Research with 2D Gel Electrophoresis
As pharmaceutical
research continues to move forward, so will the tools and techniques that are
used to evaluate proteins. At Kendrick Labs, Inc., we are committed to keeping
at the forefront of the technology used to analyze proteins. Continuing to
invest in high-performance equipment and expertise, we ensure that our 2D Gel
Electrophoresis services are among the best in the world.
For the researchers
who wish to break through in drug development or understand complex disease
mechanisms, 2D Gel Electrophoresis is a highly valuable tool. Explore here our
services and help advance your research.
Call or email us
today for more information about our services or
to discuss how we can assist with your next pharmaceutical project.
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